Today, infectious diseases remain the leading source of preventable death around the world. Compounding this problem, reliable diagnostics are often difficult to access. Current methods can take time, and they cannot always detect diseases early enough for the best treatment outcomes.
Recently, researchers explored whether metabolomics could help identify infections sooner. Metabolomics is the study of small molecules called metabolites. These molecules can serve as biomarkers, showing signs of infection within the body.
To evaluate how well metabolomics works for disease detection, researchers conducted a systematic review and meta-analysis. Their review covered studies published from 2014 to 2025. Across these studies, researchers examined whether metabolomics biomarkers could accurately identify bacterial, viral, and parasitic infections.
In their findings, researchers showed that metabolomics biomarkers were reliable diagnostic aids. In particular, they showed promise in detecting diseases during early stages of infection. Accordingly, researchers suggest that metabolomics could become an additional tool alongside more traditional diagnostic methods.










