Passport Health logo
canada flag
Afficher en français
VACCINATIONS|FIND A TRAVEL CLINIC|ADVICE
  • Home
    • About
        • Company History
        • Careers
        • Contact Us
        • Customer Feedback
        • FAQ
        • Mission Statement
        • Privacy Policy
        • Blog
    • Close
  • Destination Advice
    • Top Destinations
        • Brazil
        • China
        • Costa Rica
        • India
        • Kenya
        • Peru
        • Philippines
        • South Africa
        • Thailand
        • Vietnam
    • Destination Advice
          • Afghanistan
          • Albania
          • Algeria
          • American Samoa
          • Andorra
          • Angola
          • Anguilla
          • Antarctica
          • Antigua and Barbuda
          • Argentina
          • Armenia
          • Aruba
          • Australia
          • Austria
          • Azerbaijan
          • Azores
          • Bahamas
          • Bahrain
          • Balearics
          • Bangladesh
          • Barbados
          • Belarus
          • Belgium
          • Belize
          • Benin
          • Bermuda
          • Bhutan
          • Bolivia
          • Bonaire
          • Bora Bora
          • Bosnia
          • Botswana
          • Brazil
          • British Virgin Islands
          • Brunei
          • Bulgaria
          • Burkina Faso
          • Burundi
          • Cambodia
          • Cameroon
          • Canada
          • Canary Islands
          • Cape Verde
          • Cayman Islands
          • Central African Republic
          • Chad
          • Chile
          • China
          • Christmas Island
          • Cocos (Keeling) Islands
          • Colombia
          • Comoros
          • Cook Islands
          • Costa Rica
          • Cote d'Ivoire
          • Croatia
          • Cuba
          • Curacao
          • Cyprus
          • Czechia
          • Democratic Republic of the Congo
          • Denmark
          • Djibouti
          • Dominica
          • Dominican Republic
          • East Timor
          • Easter Island
          • Ecuador
          • Egypt
          • El Salvador
          • Equatorial Guinea
          • Eritrea
          • Estonia
          • Eswatini
          • Ethiopia
          • Falkland Islands
          • Faroe Islands
          • Fiji
          • Finland
          • France
          • French Guiana
          • French Polynesia
          • Gabon
          • Gambia
          • Georgia
          • Germany
          • Ghana
          • Gibraltar
          • Greece
          • Greenland
          • Grenada
          • Guadeloupe
          • Guam
          • Guatemala
          • Guinea-Bissau
          • Guinea
          • Guyana
          • Haiti
          • Hawaii
          • Honduras
          • Hong Kong
          • Hungary
          • Ibiza
          • Iceland
          • India
          • Indonesia
          • Iran
          • Iraq
          • Ireland
          • Israel
          • Italy
          • Jamaica
          • Japan
          • Jordan
          • Kazakhstan
          • Kenya
          • Kiribati
          • Kosovo
          • Kuwait
          • Kyrgyzstan
          • Laos
          • Latvia
          • Lebanon
          • Lesotho
          • Liberia
          • Libya
          • Liechtenstein
          • Lithuania
          • Luxembourg
          • Macao
          • Madagascar
          • Madeira Islands
          • Malawi
          • Malaysia
          • Maldives
          • Mali
          • Malta
          • Marshall Islands
          • Martinique
          • Mauritania
          • Mauritius
          • Mayotte
          • Mexico
          • Micronesia
          • Moldova
          • Monaco
          • Mongolia
          • Montenegro
          • Montserrat
          • Morocco
          • Mozambique
          • Myanmar
          • Namibia
          • Nauru
          • Nepal
          • Netherlands
          • New Caledonia
          • New Zealand
          • Nicaragua
          • Niger
          • Nigeria
          • Niue
          • Norfolk Island
          • North Korea
          • North Macedonia
          • Northern Mariana Islands
          • Norway
          • Oman
          • Pakistan
          • Palau
          • Palestinian Territories
          • Panama
          • Papua New Guinea
          • Paraguay
          • Peru
          • Philippines
          • Pitcairn Islands
          • Poland
          • Portugal
          • Puerto Rico
          • Qatar
          • Republic of the Congo
          • Réunion
          • Romania
          • Russia
          • Rwanda
          • Saba
          • Saint Barthelemy
          • Saint Helena
          • Saint Kitts and Nevis
          • Saint Lucia
          • Saint Martin
          • Saint Pierre-et-Miquelon
          • Saint Vincent and the Grenadines
          • Samoa
          • San Marino
          • Sao Tome and Principe
          • Saudi Arabia
          • Senegal
          • Serbia
          • Seychelles
          • Sierra Leone
          • Singapore
          • Sint Eustatius
          • Slovakia
          • Slovenia
          • Solomon Islands
          • Somalia
          • South Africa
          • South Georgia and the South Sandwich Islands
          • South Korea
          • South Sudan
          • Spain
          • Sri Lanka
          • Sudan
          • Suriname
          • Sweden
          • Switzerland
          • Syria
          • Tahiti
          • Taiwan
          • Tajikistan
          • Tanzania
          • Thailand
          • Togo
          • Tokelau
          • Tonga
          • Trinidad and Tobago
          • Tunisia
          • Türkiye
          • Turkmenistan
          • Turks and Caicos Islands
          • Tuvalu
          • U.S. Virgin Islands
          • Uganda
          • Ukraine
          • United Arab Emirates
          • United Kingdom
          • United States
          • Uruguay
          • Uzbekistan
          • Vanuatu
          • Vatican
          • Venezuela
          • Vietnam
          • Wake Island
          • Western Sahara
          • Yemen
          • Zambia
          • Zimbabwe
    • Close
  • Travel Medicine
    • Travel Medical Services
        • Vaccines for Travel
        • Travel Health Consulting
        • Travellers’ Diarrhea Kits
        • Dengue Fever Prevention
        • Malaria Medication
        • Zika Virus Prevention
        • Ebola Virus
        • Coronavirus
    • Close
  • Vaccinations
    • Key Travel Vaccines
      • Typhoid
      • Yellow Fever
      • Hepatitis A
      • Rabies
      • Japanese Encephalitis
      • Drug Identification Numbers (DIN)
    • Other Travel Vaccines
      • Cholera (Dukoral)
      • Chikungunya
      • Hepatitis B
      • Malaria Information
      • Meningitis
      • Polio
    • Routine Vaccinations
      • Tetanus-Diphtheria-Pertussis
      • Measles – Mumps – Rubella (MMR)
      • Pneumonia
      • Shingles
      • Influenza (The Flu)
    • Close
  • Other Services
    • Additional Services
      • TB Tests
      • Physician Referral Program
    • Close
  • For Employers
    • Corporate Wellness Solutions
      • Travel Medicine & Vaccinations
      • Onsite Flu Clinics
      • Onsite Vaccination Clinics
      • Biometric Screenings
      • Vaccine Credentialing
    • Close
  • Locations
        • Ontario
          Barrie Travel Clinic
          Brampton Travel Clinic
          Carlington - Ottawa Travel Clinic
          Downtown - Ottawa Travel Clinic
          Etobicoke Travel Clinic
          Hamilton Travel Clinic
          Kingston Travel Clinic
          Kitchener Travel Clinic
          London Travel Clinic
          Markham Travel Clinic
          Mississauga Travel Clinic
          North York Travel Clinic
          Oakville Travel Clinic
          Richmond Hill Travel Clinic
          St. Catharines Travel Clinic
          Toronto Travel Clinic
          Vaughan Travel Clinic
          Whitby Travel Clinic
          Yorkville Travel Clinic
        • Alberta
          Chinook - Calgary Travel Clinic
          Downtown Calgary Travel Clinic
          Downtown Edmonton Travel Clinic
          Southeast Edmonton Travel Clinic
          St. Albert Travel Clinic
        • British Columbia
          Burnaby Travel Clinic
          Downtown Vancouver Travel Clinic
          North Vancouver Travel Clinic
          Richmond Travel Clinic
          Surrey Travel Clinic
        • Quebec
          Clinique Santé-Voyage Centre-Ville Montréal
          Clinique Santé-Voyage Laval
          Clinique Santé-Voyage Pointe-Claire
          Clinique Santé-Voyage Ville de Québec
          Clinique Santé-Voyage Westmount
    • Close

How Much Does it Cost to Develop a New Vaccine? Who Funds the Cost?

November 10, 2023 by Ann Rapier


With the increased demand for vaccines, you may be wondering how much a vaccine costs to develop. Many factors affect the development and cost of a new vaccine. For example, research and development, clinical trials, and unsuccessful vaccine prototypes.

When there is enough demand for a vaccine, companies begin the research and development phase. The research and development phase of vaccines can take several years and millions of dollars to complete. Research and development for vaccines is one of the most costly aspects of development. Many times high and mid-range-income countries have financed the development of vaccines while low-income countries adopt the vaccines after the research has been completed.

The cost of developing a vaccine—from research and discovery to product registration—is estimated to be between US $200 million and US $500 million per vaccine. Research and development costs are the bulk of the costs. To help explain this, trial phases for two different rotavirus vaccine candidates were $137M-$206M (Merck) and $128M-$192M (GSK). But the costs of a vaccine are more than just the costs of the Phase I-III trials. Vaccine production costs per unit can be reduced significantly through gains in productivity (the “learning curve”) and economies of scale.

The costs to conduct clinical trials on a drug are higher than those to conduct the preclinical phase because trials involve the contributions of many more people for a longer time. Clinical trials occur in several phases.

Spending averaged $28 million in Phase I, $65 million in Phase II, and $282 million in Phase III. For each drug that completed the first three phases of clinical trials, the average total cost of those trials was about $375 million.

When a vaccine fails a trial, the makers have to reinvest and investigate where the failure originated. This can ultimately be the end of some vaccines. In one sample of drugs in clinical trials, researchers found that for every 100 drugs entering Phase I trials, around 60 advanced to Phase II trials, just over 20 entered Phase III trials, and only about 12 gained FDA approval.

It is also important to consider who pays for vaccine development. The federal government is the primary funder of basic research in biomedical sciences. Secondary funding could be from private sources such as Vaccine Forward Initiative, Coca-Cola, and Toyota to name a few. Regardless of who funds the vaccines, the risks of research and development remain high.

Passport Health offers a variety of vaccination and physical services to help you stay safe and healthy at home and abroad. Call 937-306-7541 or book online to schedule your appointment today.

Written for Passport Health by Brittany Evans. Brittany is a freelance writer and photographer in North Carolina. She has a passion for the outdoors, health information, and traveling. You can find her at her website.

Filed Under: General Posts

About Us

Passport Health's blog provides travelers and travel enthusiasts with a variety of news and features. We focus on bringing the most interesting and relevant stories right to our readers. Topics range from the vaccines needed for a destination to updates on recent outbreaks, travel advice and much more. Feel free to check out some of our most popular posts, linked in the sidebar, or our most recent posts below

Recent Blog Posts

  • Ruthless Marburg Outbreak in Tanzania: Its Spread and Survival Rate
  • New Research Shows How Oysters Can Help Destroy Hazardous Bacteria
  • Enormous Risk as Childhood Vaccinations Plummet: Results could be Devastating
  • New Research on Chronic Wasting Disease: A Growing Threat

Blog Archives

  • About Us
  • Contact Us
  • PIPEDA Policy and Consent Form
  • Privacy Policy
  • Automatic Data Collection Statement
  • Sitemap
Schedule Your Appointment
Questions? Please call or E-mail Us
Connect With Us:
Passport Health Canada on Facebook
Passport Health on Twitter
Passport Health on YouTube
Passport Health on Instagram
Passport Health on Linked In
Passport Health Feed

Passport Health is an Outlier business Passport Health es una empresa que pertenece al grupo Outlier Passport Health est une entreprise du groupe Outlier Copyright © 2025

This website or its third-party tools use cookies to improve functionality and performance. By continuing to browse this site, you are consenting to the use of cookies illustrated in our automatic data collection statement.Accept